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The party has no votes to spare in the Senate, and can only stomach the loss of three in the House, making the process to assuage the ideologically diverse caucus all the more important in the days ahead. Democrats intend to move both packages together to stave off an internal revolt. Left-leaning lawmakers, Amiloride and Hydrochlorothiazide (Moduretic)- Multum by the roughly 100-member Congressional Progressive Caucus, have threatened to oppose the infrastructure bill unless they can first adopt a sprawling spending measure that addresses some of their long-held priorities, including providing paid leave to nearly all working Americans and combating climate change.

She also pledged she would only bring the tax-and-spending bill to a vote before the House if it was clear it had sufficient support in the Senate, a commitment Pelosi reiterated late Monday. Three Democratic aides to Pelosi and other House leaders said they ultimately expect to resolve the differences, citing the fact that the same political fissures tend to surface around every major spending initiative.

Both have signaled they would vote against a bill at that size, with Manchin at times publicly suggesting he may only support legislation that is half that amount. Some already are discussing ways to shave money from the total amount, such as by limiting the number of weeks Amiloride and Hydrochlorothiazide (Moduretic)- Multum Americans can obtain paid leave or further restricting new child tax benefits to families with lower incomes.

Manchin earlier this month even went as far as to say he wanted to link the child tax payment to new education and work requirements, drawing widespread criticism from lawmakers within his own party. Her office did not respond to Pentoxifylline (Trental)- FDA request for comment.

An influential centrist in the chamber, Murphy already has cast a slew of protest votes as the House Ways and Means Committee assembled its portion of the legislation, including tax increases on major corporations and wealthy Americans. Democratic leaders since then have insisted they covered the costs of their new spending in full, pointing to its tax increases as well as a broader belief that their investments would result in future economic gains.

Murphy, however, said later she still had her doubts, joining a growing roster of moderates who have questioned the math in recent days.

But a collection of centrist-leaning Democrats led by Rep. The vote did not doom the drug pricing plan outright, as party leaders have other ways to ensure its inclusion. Amiloride and Hydrochlorothiazide (Moduretic)- Multum it still served as an early marker for even tougher Amiloride and Hydrochlorothiazide (Moduretic)- Multum to come as Democrats forge ahead in the Amiloride and Hydrochlorothiazide (Moduretic)- Multum. In a recent interview, Peters stressed he does support pricing reforms, just a more scaled back version that he said would preserve the ability of pharmaceutical giants to price their drugs accordingly during the exclusive, early period when they produce new medicines.

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